Plant Transcription Factor Database
Previous version: v3.0
Vitis vinifera
WRKY Family
Species TF ID Description
GSVIVT01000752001WRKY family protein
GSVIVT01001286001WRKY family protein
GSVIVT01001332001WRKY family protein
GSVIVT01007006001WRKY family protein
GSVIVT01008046001WRKY family protein
GSVIVT01008553001WRKY family protein
GSVIVT01009441001WRKY family protein
GSVIVT01010525001WRKY family protein
GSVIVT01011356001WRKY family protein
GSVIVT01011472001WRKY family protein
GSVIVT01012196001WRKY family protein
GSVIVT01012682001WRKY family protein
GSVIVT01014854001WRKY family protein
GSVIVT01015952001WRKY family protein
GSVIVT01018300001WRKY family protein
GSVIVT01019109001WRKY family protein
GSVIVT01019419001WRKY family protein
GSVIVT01019511001WRKY family protein
GSVIVT01020060001WRKY family protein
GSVIVT01020864001WRKY family protein
GSVIVT01021252001WRKY family protein
GSVIVT01021397001WRKY family protein
GSVIVT01021765001WRKY family protein
GSVIVT01022067001WRKY family protein
GSVIVT01022245001WRKY family protein
GSVIVT01022259001WRKY family protein
GSVIVT01023600001WRKY family protein
GSVIVT01024624001WRKY family protein
GSVIVT01025491001WRKY family protein
GSVIVT01025562001WRKY family protein
GSVIVT01026965001WRKY family protein
GSVIVT01026969001WRKY family protein
GSVIVT01027069001WRKY family protein
GSVIVT01028129001WRKY family protein
GSVIVT01028147001WRKY family protein
GSVIVT01028244001WRKY family protein
GSVIVT01028718001WRKY family protein
GSVIVT01028823001WRKY family protein
GSVIVT01029265001WRKY family protein
GSVIVT01029688001WRKY family protein
GSVIVT01030046001WRKY family protein
GSVIVT01030174001WRKY family protein
GSVIVT01030258001WRKY family protein
GSVIVT01030453001WRKY family protein
GSVIVT01032661001WRKY family protein
GSVIVT01032662001WRKY family protein
GSVIVT01033063001WRKY family protein
GSVIVT01033188001WRKY family protein
GSVIVT01033194001WRKY family protein
GSVIVT01033195001WRKY family protein
GSVIVT01034148001WRKY family protein
GSVIVT01034968001WRKY family protein
GSVIVT01035426001WRKY family protein
GSVIVT01035884001WRKY family protein
GSVIVT01035885001WRKY family protein
GSVIVT01035965001WRKY family protein
GSVIVT01036223001WRKY family protein
GSVIVT01037686001WRKY family protein
GSVIVT01037775001WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701